What is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide — a 15-amino-acid sequence derived from a larger gastric protein. It has been the subject of extensive research due to its unique biological properties.
The peptide sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Research Areas of Interest
Tissue Response Studies
Multiple rodent studies have examined BPC-157's effects on various tissues including muscle, tendon, ligament, and gastrointestinal tissues. Research has explored its role in tissue repair pathway modulation.
Gastrointestinal Studies
As a gastric-derived peptide, BPC-157 has been extensively studied in models of GI damage, including ulcerative and inflammatory models.
Neurological Research
Emerging research has investigated potential neuroprotective properties and effects on dopaminergic and serotonergic systems.
Mechanisms Under Investigation
- Angiogenesis — Promotion of new blood vessel formation
- Growth factor modulation — Effects on VEGF, EGF, and other factors
- Nitric oxide pathways — Interaction with NO system
- FAK-paxillin pathway — Cell migration and tissue organization
Research-Only Status
BPC-157 is sold for laboratory research purposes only. It has not been approved by the FDA for human use.
Stability Considerations
BPC-157 is known for its exceptional stability compared to many peptides:
- Highly stable in gastric juice (pH 2)
- Resistant to enzymatic degradation
- Stable in reconstituted solution for extended periods