Quality Control at Every Step
Maintaining peptide quality requires attention from procurement through experimental use. A comprehensive QC approach ensures reliable, reproducible results.
Incoming Material Verification
Document Review
- Verify COA matches batch number on vial
- Confirm purity meets your requirements
- Check molecular weight against expected value
- Review storage conditions during shipping
Visual Inspection
- Check for intact seal and cap
- Examine lyophilized cake appearance (should be white/off-white)
- Look for signs of moisture exposure or discoloration
In-Lab Testing Options
UV Spectroscopy
Quick verification of peptide concentration using absorbance at 280nm (for peptides containing aromatic amino acids).
pH Measurement
Verify reconstituted solution pH matches expected range for stability.
Visual Clarity
Reconstituted peptide should be clear. Cloudiness or particles indicate potential degradation or contamination.
Documentation Best Practices
- Log all incoming peptides with batch numbers
- Record reconstitution dates and volumes
- Note storage locations and temperature monitoring
- Track aliquots and usage dates
- Maintain chain of custody for GLP studies
Retention of Reference Samples
Keep a small amount of each batch unused and frozen. This allows re-testing if experimental results are questioned.