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NAD+

infoResearch Use Only

This product is intended solely for use as a research chemical in vitro and laboratory experimentation. Not for human use.

Overview

Nicotinamide Adenine Dinucleotide (NAD+) is a critical coenzyme found in every living cell, serving as an essential cofactor for numerous metabolic reactions. This dinucleotide consists of two nucleotides joined through their phosphate groups, with one nucleotide containing an adenine base and the other containing nicotinamide.

**MECHANISM OF ACTION:** NAD+ functions as a crucial electron carrier in cellular metabolism, participating in over 500 enzymatic reactions. It serves as a substrate for sirtuins (SIRT1-7), poly-ADP-ribose polymerases (PARPs), and CD38, enzymes critically involved in DNA repair, gene expression regulation, and cellular stress responses. The NAD+/NADH ratio is a key indicator of cellular metabolic state and redox balance.

**RESEARCH APPLICATIONS:** - Sirtuin Activation Studies - Cellular Energy Metabolism Research - DNA Repair Mechanism Investigations - Mitochondrial Function Analysis - Circadian Rhythm Regulation Studies - Epigenetic Modification Research - Aging and Longevity Pathway Studies

**SCIENTIFIC BACKGROUND:** Seminal research published in Cell, Nature, and Science has demonstrated the importance of NAD+ in cellular homeostasis. Studies from institutions including Harvard Medical School and MIT have explored NAD+ precursor supplementation and its effects on metabolic parameters. The "NAD World" concept describes the interconnected network of NAD+-consuming enzymes and their biological significance.

**TECHNICAL SPECIFICATIONS:** - Molecular Formula: C21H27N7O14P2 - Molecular Weight: 663.43 g/mol - CAS Number: 53-84-9 - Form: Lyophilized powder, hygroscopic - Purity: >98% (enzymatic assay)

**QUALITY ASSURANCE:** Each batch undergoes enzymatic activity verification, HPLC purity analysis, and endotoxin testing.

FOR RESEARCH USE ONLY. Not for human consumption.

Research Use Only. This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or veterinary use.

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Our proprietary synthesis and purification processes ensure >99% purity for reliable research outcomes.

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Every batch undergoes rigorous third-party HPLC and MS testing. Certificates of Analysis provided with every order.

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