infoResearch Use Only
This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or animal consumption.
Reta
infoResearch Use Only
This product is intended solely for use as a research chemical in vitro and laboratory experimentation. Not for human use.
Overview
Retatrutide is a novel triple agonist peptide targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors. This first-in-class triple hormone receptor agonist represents the next evolution in multi-receptor metabolic peptide research, building upon the dual agonist approach with the addition of glucagon receptor activity.
**MECHANISM OF ACTION:** Retatrutide's triple agonist profile provides a unique pharmacological approach to metabolic research. GLP-1 and GIP receptor activation promotes incretin-mediated effects, while glucagon receptor stimulation may contribute to energy expenditure and lipid oxidation pathways. The glucagon component differentiates retatrutide from dual agonists and may contribute to enhanced metabolic effects observed in clinical studies.
**RESEARCH APPLICATIONS:** - Triple Incretin Pathway Studies - Energy Expenditure Mechanism Research - Hepatic Glucose Output Modulation - Lipid Oxidation Pathway Analysis - Appetite Signaling Research - Body Composition Studies - Metabolic Rate Investigations
**CLINICAL RESEARCH SIGNIFICANCE:** Phase 2 clinical trial data published in the New England Journal of Medicine demonstrated dose-dependent effects on metabolic parameters. The triple agonist mechanism is under active investigation for its potential synergistic effects compared to single or dual receptor approaches.
**TECHNICAL SPECIFICATIONS:** - Receptor Targets: GLP-1R, GIPR, GCGR - Form: Lyophilized powder - Purity: >97% (HPLC) - Storage: -4F (-20C) lyophilized; 36-46F (2-8C) reconstituted
**QUALITY ASSURANCE:** Third-party verified for identity, purity, and sterility. Certificate of Analysis available.
FOR RESEARCH USE ONLY. Not for human consumption.
Research Use Only. This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or veterinary use.
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