For research and educational purposes only. PepTalk discusses what researchers study in laboratory settings — not medical advice. Products are sold for laboratory research use only.
Research Compound
5-Amino-1MQ
A small-molecule NNMT inhibitor studied for fat-cell metabolism and the NAD+ pathway — freeze-dried, ultra-pure, ready to reconstitute.
For research and educational purposes only. PepTalk discusses what researchers study in laboratory settings — not medical advice. Products are sold for laboratory research use only.
The short version
5-Amino-1MQ isn't a peptide — it's a small molecule studied for one specific job: blocking an enzyme called NNMT inside fat cells. NNMT quietly burns through nicotinamide, the raw material cells use to make NAD+. By inhibiting it, researchers study whether fat cells hold onto more NAD+ and shift into a more metabolically active state.
What researchers are looking at
Fat cells contain an enzyme called NNMT (nicotinamide N-methyltransferase). Its job is to neutralize nicotinamide — a building block the cell would otherwise convert into NAD+, the coenzyme at the center of cellular energy. When NNMT is highly active, fat cells end up with less NAD+ and sit in a quieter, less metabolically active state.
5-Amino-1MQ is a selective inhibitor of that enzyme. In research models, blocking NNMT preserves the nicotinamide the cell would have wasted, which researchers study as a route to raising NAD+ availability inside the fat cell. Higher NAD+ is in turn studied for activating SIRT1 and AMPK — proteins tied to fat breakdown and metabolic rate.
It's one of the few research compounds that targets fat-cell metabolism at the NAD+ precursor level rather than supplementing NAD+ directly. This work is at the enzyme-and-cell level — best read as what researchers observe about NNMT and the NAD+ pathway in their models, not proven outcomes.
NNMT blocked
5-Amino-1MQ selectively inhibits the NNMT enzyme, stopping it from consuming nicotinamide in fat cells.
NAD+ precursor preserved
The spared nicotinamide is free to be converted to NAD+, raising its availability inside the cell.
Metabolic switches studied
Higher NAD+ is studied for activating SIRT1 and AMPK, the pathways tied to fat breakdown and metabolic rate.
Where the evidence stands
an honest mapEnzyme- and cell-level NNMT/NAD+ research
Preclinical; no controlled human trials
At a glance
What it is
A small-molecule inhibitor
NNMT inhibitor, not a peptide
Studied for
Fat-cell metabolism
NAD+ pathway, NNMT
Mechanism
Blocks NNMT
preserves NAD+ precursor
Research stage
Preclinical
enzyme & cell models
How it arrives
Lyophilized powder
Ships freeze-dried for stability and shelf life. Before research use, it's reconstituted with bacteriostatic water. Store the lyophilized vial at -20°C, protected from light; once reconstituted, keep at 2–8°C and use within 28 days.
Bacteriostatic water
Needed to reconstitute
Certificate of analysis
Common questions
All products on FastPeps are labeled Research Use Only (RUO), and this is a legal requirement, not just fine print. It means these compounds are sold strictly for scientific research and laboratory purposes, not for personal use, self-administration, or medical treatment. This label exists because these compounds have not completed the FDA approval process to be sold as drugs or supplements. When you purchase from FastPeps, you are agreeing the product is for research purposes only.
For laboratory and research use only. Sold exclusively for in-vitro research and laboratory experimentation. Not a drug, supplement, or article intended for human or veterinary use; nothing here is medical advice or a claim of therapeutic benefit. Statements describe findings from published research.
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