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Reta / Cagri Blend — image 1 of 2

Metabolic research

Reta / Cagri Blend

Reta (5mg) and Cagri (5mg) in a single vial: a triple-receptor agonist paired with a long-acting amylin analog. Freeze-dried, ≥99% per component.

Save up to 30% on Reta / Cagri Blend.

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Peptide Dialogues podcast

For research and educational purposes only. PepTalk discusses what researchers study in laboratory settings, not medical advice. Products are sold for laboratory research use only.

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The short version

This blend combines two of the most-watched compounds in metabolic research. Reta acts on three receptors at once (GIP, GLP-1 and glucagon). Cagri is a long-acting version of amylin, a separate fullness signal. Pairing an incretin-based compound with an amylin analog is one of the most active areas in current metabolic research.

Metabolic researchSatiety signalingTriple agonist + amylin

What researchers are looking at

Reta is a triple-receptor agonist. Two of its pathways, GIP and GLP-1, are studied for reducing hunger signaling and improving how the body handles insulin. The third, glucagon, is studied for raising energy expenditure and mobilizing fat stored in the liver.

Cagri works through a completely different system. Amylin is a hormone released alongside insulin after a meal, and it signals fullness through its own receptors in the brain. Natural amylin breaks down quickly; Cagri is a long-acting analog built to last much longer, so researchers can study sustained amylin signaling.

Because the two compounds act on separate pathways, combining them lets researchers study whether incretin and amylin signals add to each other. Each compound has been studied on its own in human clinical research, while this specific two-in-one combination is a newer research area.

01Step

Three receptors

Reta acts at GIP, GLP-1 and glucagon receptors, studied for appetite, insulin handling and energy expenditure.

02Step

A separate fullness signal

Cagri is a long-acting amylin analog, studied for satiety signaling through its own receptors in the brain.

03Step

Studied together

Researchers combine them to ask whether incretin and amylin signals add to each other.

Where the evidence stands

an honest map
Preclinical · animal & labStrong

Both components well characterized in metabolic models

Human · clinicalModerate

Each studied individually in human trials; the combination is newer

At a glance

What it is

A two-compound blend

Reta 5mg + Cagri 5mg

Studied for

Appetite and energy use

metabolic research

Pathways

Four in total

GIP, GLP-1, glucagon, amylin

Research stage

Components in human trials

combination is newer

How it arrives

Lyophilized powder

Ships freeze-dried in a single vial. Before research use, it's reconstituted with bacteriostatic water. Once reconstituted, keep it refrigerated and use within the window noted on the Certificate of Analysis.

Bacteriostatic water

Needed to reconstitute

Certificate of analysis

Third-party verified · this batch
Purity ≥99% (HPLC) for each componentHPLC · MS

Common questions

They work through different systems. Reta acts on the GIP, GLP-1 and glucagon receptors, while Cagri acts on amylin receptors. Combining them lets researchers study whether those signals add to each other.

For laboratory and research use only. Sold exclusively for in-vitro research and laboratory experimentation. Not a drug, supplement, or article intended for human or veterinary use; nothing here is medical advice or a claim of therapeutic benefit. Statements describe findings from published research.

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